This study objective was to determine the effect on remission of prediabetes with a high protein (HP) versus high carbohydrate (HC) diet, and effects on metabolic parameters, and lean and fat body mass in prediabetic, obese subjects after 6 months of dietary intervention. They recruited women and men ages 20–50 years with a BMI ≥ 30 to ≤55 kg/m2 with prediabetes for a total of 24 participants.