Artificial Pancreas

Singularity Hub – Bionic Pancreas Promises Big Boost in Health for TI

A bionic pancreas whose first results in human patients were recently published in the New England Journal of Medicine, could make the statement purely factual: If you have type 1 diabetes, you will have to prick yourself once every four days or so to change out the needles in the closed-loop blood sugar monitor and […]

ADA: Bionic Pancreas Effective in Reducing Glucose Over Multiple Days

An automated “bionic” pancreas that incorporates glucagon as well as insulin has shown improved blood glucose for five consecutive days in a study of patients with type 1 diabetes.

Medical News Today – Treatment could spur production of insulin in Type 1 diabetes

Combining two different medications could help patients with Type 1 diabetes at least partially regain the ability to produce their own insulin, a University of Florida study has shown.

Insulin Nation – An Endocrinologist’s Frustration with Insulin Therapy

The bionic pancreas requires patients wear two insulin pumps, one containing insulin and the other containing glucagon, a well as a glucose sensor. A brilliant computerized algorithm hooked to an iPhone is used to pump both insulin and glucagon based on each glucose reading. Will this be enough to overcome the challenges of insulin therapy?

Insulin Nation – Teens Try Artificial Pancreases at Home

In April 2014, researchers with the Juvenile Diabetes Research Foundation UK announced the success of a study that allowed teens with Type 1 diabetes to test artificial pancreas technology in real world conditions.

DiabetesMine – GlySens (Still) Developing Implantable CGM (See Also: ICGM)

The small 16-year-old startup is developing an implantable CGM dubbed ICGM, which in its second incarnation uses a sensor that looks like a fat thumb drive with a quarter-sized circle in the middle.

Associated Press – Stem Cell Advance May Bring New Diabetes Treatments

In a potential step toward new diabetes treatments, scientists used a cloning technique to make insulin-producing cells with the DNA of a diabetic woman. The approach could someday aid treatment of the Type 1 form of the illness, which is usually diagnosed in childhood and accounts for about 5 percent of diabetes cases in the […]

Medical News Today – Breakthrough artificial pancreas study

The University of Cambridge-devised artificial pancreas promises to dramatically improve quality of life of people with type 1 diabetes, which typically develops in childhood. The latest trial, coordinated by the University and funded by JDRF, has shown for the first time globally that unsupervised use of the artificial pancreas overnight can be safe – while […]

Huffpost – Turning Diabetes Over to the Bionic Pancreas

The bionic pancreas consists of three pieces of hardware. There’s an iPhone with an app that contains the system’s control software and algorithm and a continuous glucose monitor (CGM).

ASweetLife – Getting Insulin from Gut Cells: Diabetes Cure Research

Imagine millions of tiny insulin pumps that work really well, measuring your blood sugar hundreds of times each second and secreting just the right amount of insulin. Ben Stanger, M.D., Ph.D., and his research team at the University of Pennsylvania believe that people with Type 1 diabetes could harbor similar cells in their gut.

Insulin Nation – I Was an Artificial Pancreas Guinea Pig!

When JDRF committed to funding research in artificial pancreas technology in 2006, Brobson raised his hand to be a guinea pig. In 2007, he began to take part in human clinical trials of artificial pancreas technology through the University of Virginia Center for Diabetes Technology.

ASweetLife – Lawrence Steinman’s ‘Reverse Vaccine’ Targets Immune Response in Type 1 Diabetes

Sometimes, when you’re stuck and spinning your wheels without making much forward progress, putting it in reverse can get you going. That’s what Dr. Lawrence Steinman and his colleagues are doing by attempting to cure type 1 diabetes with a unique and groundbreaking “reverse vaccine.”

BattleDiabetes – 10 years of being diabetes-free, thanks to pancreatic islet cell transplants

Two patients from Emory University School of Medicine celebrated a huge milestone recently – 10 years of being diabetes-free after receiving transplants of donor pancreatic islet cells.

Joslin Diabetes – Making Beta Cells

A new technique developed over the last decade can take skin cells, or any other cells of the body, and make them into something new. This process holds promise for the damaged pancreas of people with diabetes.

Insulin Nation – How to Protect Transplanted Islets

Any islets transplanted into the T1 body must run a gauntlet of killer T cells to survive long enough to integrate into the body. Most don’t live that long; some 90% of islets die either during transplant or shortly thereafter, making islet therapy often an expensive T1 therapy of last resort.

Insulin Nation – Islet Therapy Gains Ground

As co-director of the Clinical Islet Transplant Program at the University of California, San Francisco (UCSF), Dr. Stock is one of the scientists on the frontline of trying to make islet therapy a viable. “We’ve been saying islet therapy is ‘right around the corner’ for quite awhile, but now it really seems to be true,” […]

DiabetesMine – Tom Brobson and His Artificial Pancreas Roadshow

As the JDRF’s national director of research investment opportunities, Tom’s one of the most sought-after speakers at the moment because he’s able to not only give an overview of the latest exciting D-tech, but also share his own personal experiences as one of the first people ever to wear an Artificial Pancreas system over a […]

Diabetes Mine – Islet Transplantation: On the Verge of Mainstream?

As someone who’s been doing islet cell transplants for 20-plus years now, Dr. Jose Oberholzer in Chicago wonders why more people with diabetes don’t know about the procedure as an option.

Type 1 Diabetes: A treatment’s in sight but where’s the funding?

Preparing for human clinical trials, the research pediatrician at Children’s Hospital of UPMC of Pittsburgh needs $7 million to $10 million for a multi-site trial involving 105 people with a recent diagnosis of type 1 diabetes. But federal budget cuts are making it difficult to land research grants through the National Institutes of Health.

US News – British Experimental ‘Implanted Insulin’ Device Seeks to Control Blood Sugar Levels

The device, which is currently dubbed “a self-regulating insulin delivery device,” would be implanted in the abdomen. The outside of the device would be made of plastic or metal and there would be no electronic or moving parts.