Drugs

Older Antiretroviral Treatments Raise Diabetes Risk for HIV Patients

For HIV-positive individuals, combination antiretroviral therapy (ART) has been a lifesaving treatment, allowing people with HIV to have near-normal life expectancies. However, these patients may have a higher risk of developing diabetes than the general population, and at earlier ages. The risk is higher for those who took older formulations of ART, and for those […]

What are Biosimilars, and What Do They Mean for Diabetes Treatment?

A biosimilar is a biological product defined as being comparable (but not identical) to an already FDA-approved biological product, in molecular structure, safety, and effectiveness. Because they are not identical to the reference product, they differ from generic drugs, which have identical molecular structures and active ingredients to those of the brand name products. The […]

Metformin Helps Heart Health for Type 1 Kids

A new study found that the diabetes medication metformin, most commonly used to treat type 2 diabetes, also has particular benefit for children with type 1 diabetes, particularly for heart health. For children with type 1 who are above average weight,  metformin provided a significant improvement in vascular smooth muscle function. Metformin also improved HbA1c […]

Sustained Lifestyle Changes, Medication Can Help Prevent Diabetes Progression

A new analysis of multiple studies examined health interventions and their effectiveness in people with prediabetes. The analysis found that changes in diet, physical activity and weight loss, along with the use of  certain insulin-sensitizing medications, can prevent progression to diabetes in at-risk individuals. However, the analysis also found that the risk rose again right […]

Liraglutide Helps Weight, Quality of Life

A new study suggests the diabetes drug liraglutide is effective in improving weight loss and quality of life in patients with obesity and prediabetes. A greater proportion of participants who lost weight over 3 years in the liraglutide group compared to the placebo group. Together with diet and exercise changes, liraglutide achieved long-term improvements in […]

“Ghost Pills” Not Just for Halloween

Have you ever heard of “ghost pills”? It’s nothing to do with Casper or poltergeists. It’s a situation you may experience with some controlled or extended release medications, such as extended release metformin. The formulation of the pills means they may look like they haven’t been “digested.” In other words, you may notice the remains […]

Discontinuing Low-Dose Aspirin Raises Heart Risk

Taking a daily dose of low-dose aspirin is widely recommended to lower the risk of heart attack. Cardiovascular issues are a common complication in patients with diabetes. A new study looked at the risk to patients who stop taking low dose aspirin. It found that risk of heart attack increased immediately after patients stopped taking […]

New Study Shows SGLT-2 Inhibitors Have Heart Benefits for Elderly

New research led by the American insurance company Anthem Inc. looked at how the SGLT-2 inhibitor drug class, which includes drugs like Invokana and Jardiance, compares to the drugs in the DPP-4 inhibitor class (such as Januvia and Tradjenta). The study found a significant reduction in heart failure hospitalizations among older patients at risk of […]

Older, Less Expensive Diabetes Drug Types Can Still be Effective

There’s been a lot in the news recently about the cardiovascular benefits of some of the newer, more expensive diabetes drugs, such as the SGLT-2 inhibitor class, which includes such brand-name drugs as Invokana and Jardiance. A recent study looked at two older, affordable, and commonly-prescribed types of drugs, to see how they compared. According […]

First Oral Drug for Type 1 Diabetes

A new oral medication for type 1 diabetes, sotagliflozin, has been developed by  Lexicon Pharmaceuticals; the company plans to file marketing applications worldwide in the first half of 2018. In trials, patients taking sotagliflozin in addition to insulin showed significant improvements in glucose control, a drop in systolic and diastolic blood pressure and weight loss. If […]

New Treatment May Help Preserve Bone Health in Diabetes

Experiments with a drug compound called TNP (also known as picric acid), used by researchers to study obesity and diabetes, show that in mice the therapy can promote the formation of new bone. This is important as many current drugs that help patients manage their diabetes can also weaken bones, leaving patients more vulnerable to […]

Metformin for Type 1?

Metformin has long been considered exclusively a drug for type 2 diabetes, not useful for insulin-dependent patients with type 1. However, new studies have shown that the drug can help patients with type 1 reduce insulin requirements, maintain tighter glucose control, and lose weight. By keeping their glucose within goal range, patients can reduce their risk […]

Semaglutide Outperforms Trulicity

A new drug from Novo Nordisk, Semaglutide, was tested in a head-to-head comparison with Eli Lilly’s Trulicity. Both medications belong to a class of drugs called GLP-1 agonists. This class of drug offers many benefits to patients with type 2 diabetes, as they can lower blood glucose while minimizing the chances of hypoglycemic events. A […]

Heart Benefits from Canagliflozen

Canagliflozin, (marketed under the brand names Invokana or Sulisent) is one of the sodium glucose cotransporter 2 (SGLT-2) inhibitor class of drugs. Introduced relatively recently, these drugs have been widely studied for both their potential complications (kidney issues and amputation risk), and potential benefits for heart health. Now the CANVAS study finds canagliflozin significantly reduces risk for cardiovascular death, […]

Is Pharma Research Doing Enough for Diabetes?

With prediabetes and type 2 on the rise in the U.S., are pharma companies doing enough to develop new treatments? Harvard researchers argue that companies are doing less R&D into diabetes drugs than would be expected given the prevalence of the disease, and suggest FDA requirements to determine the cardiovascular safety of new drugs may […]

Osteoporosis and Diabetes

When it comes to increased risk of osteoporosis, not all diabetes drugs are the same. A new study looks at the connections between diabetes and osteoporosis, and suggests certain types of drugs should be avoided to reduce risk of bone loss. Read more

Can Metformin Really Slow Aging?

The diabetes drug metformin is reputed to have many beneficial effects. Researcher Nir Barzilai, director of the Institute for Aging Research at the Albert Einstein College of Medicine in the Bronx, New York, believes it may be able to help us extend our years of healthy, illness-free life. Read more.

A New Solution for Monitoring Insulin Temperature

Amin Zayani has had type 1 diabetes for 11 years and relies on daily insulin injections. A couple of years ago he had a bad experience when his insulin suddenly seemed to stop working. He discovered that the cause was that, unknown to him, his insulin had frozen in the refrigerator, ruining its potency. To keep […]

Diabetes Drug Canagliflozin Shows Heart Benefits

Canagliflozin (marketed under the brand name Invokana) is one of a newer class of diabetes drugs, the SGLT-2 Inhibitors, that have received much attention in the last few years.  Now a new study shows that patients taking canagliflozin have a significantly reduced risk of heart attacks and strokes when compared to placebo. Since most patients […]

Diabetes Drug Shows Benefits for Heart & Kidney Disease

A new study from Australia reports that the diabetes drug canagliflozen may have benefits beyond lowering blood sugar in patients with type 2 diabetes. It also may lower the risk of cardiovascular disease (CVD) and kidney disease significantly. Read more