Glucose & Insulin

Intensive Insulin Therapy Increases Retinopathy Risk for Some

While insulin therapy reduces the overall incidence of diabetic retinopathy and other diabetic complications, intensive insulin therapy with rapid glycemic reduction could actually worsen retinopathy progression in some patients. Healthcare professionals should assess patient’s current retinopathy status before selecting the type of insulin and intensiveness of treatment. Read more

FDA Approves First “Artificial Intelligence” Insulin Pen Cap

The FDA has cleared The Bigfoot Unity AI Diabetes Management System by Bigfoot Biomedical, an artificially intelligent insulin pen cap, for use in type 1 and type 2 diabetes patients aged 12 or older. The device has the potential to make insulin dosing much less burdensome for many patients. Read more

Does Insulin Worsen Cardiac Risk in Type 2 Diabetes?

While insulin is the standard treatment for type 1 diabetes, it is also used for type 2 diabetes patients who are unable to reach their glycemic target with other medications. As the number of patients with type 2 prescribed insulin is growing, researchers sought to understand whether the risk for hypoglycemia associated with insulin could […]

Blood Glucose and Brain Health in Prediabetes

Hyperglycemia has long been associated with risks to cognitive function in people with diabetes. Now a new analysis suggests that patients with prediabetes have a similar risk for declines in brain function to patients already diagnosed with diabetes, making good glucose control important in the prediabetes stage. Read more

Rising Insulin Prices for Many Patients

Several pharma companies withdrew from the US Federal government’s 340B drug pricing program last fall, which has left many patients with diabetes struggling to cope with surging insulin prices, or having to use less effective versions of insulin, says Anne Webster, NP. Read more

How Diabetes Affects the Cornea

Diabetes patients who are older, who have had the disease for at least 10 years, and/or have high glycated hemoglobin (A1C), are likely to have damage to corneal endothelial cells, researchers say. The results support the need for patients with diabetes to have regularly-scheduled corneal endothelial examinations. Read more

Insulin Dosing Before Exercise

Exercise is essential for people with diabetes, but it also can contribute to variations in blood sugar levels, depending on the type of exercise, duration, and many other factors. A small pilot study suggests that low insulin with modest hyperglycemia may be better than higher insulin levels when exercising with type 1 diabetes. Read more

Is Fully Automated Insulin Delivery on the Horizon?

Currently available closed loop insulin delivery systems (sometimes called the “artificial pancreas”) have made insulin dosing much easier for many people with diabetes. However, they still require users to monitor data and take various daily actions. One innovator is looking to develop a fully automated system that would not require any manual tasks, such as […]

Zegalogue Glucagon Rescue Pen Receives FDA Approval

Zegalogue will be sold as both an auto-injector, similar to an EpiPen, and a prefilled syringe, and will allow people with diabetes to quickly raise their blood sugars in an emergency situation. It is approved for adults and for children 6 and up, and is expected to launch in June 2021. Read more

ADA Urges Stricter A1c Guidelines for Children with Type 1

The American Diabetes Association (ADA) recommends lowering the target hemoglobin A1C (HbA1C) guidelines for children with type 1 diabetes. This is due to the finding that chronically high blood glucose levels in children could lead to higher risk of several serious effects, including abnormal brain development and cardiac issues. Read more

No-Refrigerator Insulin in Development

Aiotech company called Thermalin is working on a new type of ultra-fast insulin that will not require refrigerated storage. They are also developing a miniaturized closed loop device (also called an artificial pancreas system) called the StampPump. Read more

COVID-19 Severity Linked to Hyperglycemia

COVID-19 patients may be at a higher risk for complications and death if their blood glucose is elevated, even if they have not been diagnosed with diabetes, researchers say. Read more

Telemonitoring as Tool for Diabetes Care

Diabetes patients who used a medical device an software system called DIABEO to help manage their insulin dosage were more successfully able to reduce their HbA1c levels, a study found, since using the telemonitoring system allowed patients more support and guidance on controlling their glucose levels. Read more

High Glucose Can Damage the Brain

Uncontrolled blood glucose in diabetes can lead to numerous debilitating complications, including high blood pressure, strokes, slow wound healing, and possibly amputations. Researchers have found that brain damage can also result from uncontrolled type 2 diabetes. Read more

Can Electromagnetic Fields Treat Diabetes?

Electromagnetic fields (EMFs) might be a safe and non-invasive way to manage blood glucose in diabetes, say researchers who examined the effects of EMFs in altering the balance of oxidants and antioxidants in the liver and causing an improvement in the body’s response to insulin. Read more

Anemia and A1c

Glycated hemoglobin (A1c) testing is a standard method of assessing blood glucose levels in people with diabetes. However, researchers are finding that iron deficiency or vitamin B12 deficiency anemia can affect A1c testing results. Read more

The Role of Weak and Strong Cells in Insulin Production

Type 2 diabetes is the condition that results when β-cells (beta cells) cannot release enough insulin for the body’s needs. A group of researchers say they have new insight into how “weak” beta cells bond with other, more mature cells to boost insulin production, which can help us understand more about the processes that lead […]

The Long-Term Risks of Severe Hypoglycemia

Severe hypoglycemia can lead to fatal complications, including heart arrhythmias, seizures, and coma. Research has also found that patients with hypoglycemic events severe enough to require medical assistance also had increased risk of developing cancer and skin, respiratory, and digestive complications. Read more

Add-on Therapy Can Reduce Insulin Use for Type 2 Patients

Insulin is the mainstay treatment for patients with type 2 diabetes who also have beta-cell failure; however, some insulin regimens can be complicated to manage and may increase the risk of hypoglycemia. Now, researchers say that a simple add-on therapy with the GLP-1 Agonist medication albiglutide can reduce insulin use for patients with type 2 […]

Potential New Target for Diabetes Treatment

Researchers have discovered a new insulin inhibitory receptor, named inceptor. (Insulin receptors are areas in human cells that allow insulin in the blood to join or bind with the cell.) The researchers found that blocking inceptor function makes the insulin signaling pathway in pancreatic beta cells more sensitive, which could potentially allow protection and regeneration […]