Glucose & Insulin

Oral Semaglutide Effective Paired with Insulin

Multiple studies have been conducted to evaluate the performance of oral semaglutide, which is the first oral medication in the glucagon-like peptide-1 (GLP-1) receptor agonist drug class. The PIONEER 8 trial found reductions in A1c and body weight when oral semaglutide is paired with various insulin regimens. Read more

A Micro Artificial Pancreas to Begin Trials

Betalin Therapeutics says that it will submit a request next month for human clinical trials in the UK for its tiny micro-pancreas that can “cure” diabetes for millions of people and eliminate the need for insulin injections. The device is designed for people with type 1 diabetes, and those with type 2 diabetes who require […]

“Metabolic Memory” of Poor Glucose Control Can Last a Lifetime

Researchers have found a strong association between early episodes of poor blood sugar control, epigenetic changes (which affect the activity of particular genes without altering their DNA sequences), and diabetic complications years later, even if patients subsequently had better glycemic control. Read more

Saliva Glucose Testing May Be Non-Invasive Alternative

Lab research suggests that saliva testing may one day offer a more cost-effective and painless alternative to finger sticks for measuring glucose levels and monitoring diabetes management. Read more

Is COVID-19 Quarantine Affecting Glucose Management?

Many countries have enacted lockdowns in order to combat the spread of coronavirus (COVID-19). These stay-at-home orders have disrupted daily routines for many diabetes patients, which has created concerns over the possible consequences of added stress, isolation, and elevated blood sugars on glucose management. Read more

Exercising and Managing Insulin with Type 1

Balancing blood glucose levels during (and after) exercise with type 1 diabetes is key if you want to be successful at being physically active as an insulin user, and want to prevent hypoglycemia or hyperglycemia during exercise. Diabetes exercise expert Dr. Sheri Colberg shares some tips for managing insulin, food, and exercise. Read more

Once-Weekly Insulin Shows Promise for Type 2

Currently there is no such thing available as a once-weekly insulin product. However, a new type of insulin, called insulin icodec, is showing promise in testing, and may one day offer people with type 2 a more convenient option for taking insulin. Read more

Glycemic Control in Young Americans with Diabetes Getting Worse

Blood glucose control among youth with diabetes has not improved since 2002 levels, and has actually gotten worse in some subgroups, according to data presented at the virtual American Diabetes Association (ADA) 2020 Scientific Sessions. This is despite increased availability of diabetes technology and new therapies in recent decades, and despite more aggressive recommended blood […]

New Insulin Hybrid Uses Sea Snails

An international team of researchers reported they have developed the world’s smallest, fully functional version of the insulin hormone. This version combines the potency of human insulin with the fast-acting potential of a venom insulin produced by predatory cone snails. Read more

New ADA Program Caps Insulin Co-pays for Medicare Recipients

The American Diabetes Association (ADA) joined the Centers for Medicare and Medicaid Services (CMS) in announcing the Part D Senior Savings Model, which will limit the cost of insulin for participating seniors to a maximum of $35 for a 30-day supply.  Read more

High Glucose Linked to Maternal Mortality

A recent study has found that elevated pre-pregnancy hemoglobin A1c, which measures average blood glucose concentration, is associated with higher risk of adverse pregnancy outcomes, even in women who have not been diagnosed with diabetes. Read more

People with Type 2 Produce Excess Glucagon

People who have type 2 diabetes do not only lack the right amount of insulin, they also produce excess glucagon, researchers say. Both these factors contribute to poor blood glucose control, researchers have said. Glucagon, which is produced by alpha cells in the pancreas, helps the body to regulate glucose and fats; both it and […]

Earlier Insulin Treatment for Type 2 Patients?

Irl B. Hirsch, MD, professor of medicine at the University of Washington in Seattle, argues that insulin treatment should begin earlier to improve outcomes for people with type 2 diabetes. While many people with type 2 have early success with standard treatment — including weight loss, diet changes, and various oral medications — the majority […]

Is Prediabetes Really Diabetes?

Researchers have found that people whose blood glucose readings are classified as prediabetes are already at increased risk for many complications of diabetes, including retinopathy, peripheral neuropathy, and diabetic nephropathy, and some experts suggest that treatment should begin far earlier to prevent these complications. Read more

Poorly Controlled Blood Sugar Increases Risk of Death for COVID-19

Researchers have found that people with diabetes and poorly managed hyperglycemia who are hospitalized for COVID-19 have a death rate, and longer length of hospital stay, four times higher than people without these conditions. Read more

Too Much Glucagon May Contribute to Type 2

Glucagon is a pancreatic hormone which contributes to glucose production. A new study found that patients with type 2 diabetes secrete not only too little insulin but also too much glucagon, which contributes to poor blood glucose control. Read more

Generic Lilly Insulins Now Available at Half Price

“Authorized generic” versions of two popular insulins made by Eli Lilly are now available to order by U.S. pharmacies, with list prices 50% lower than the Lilly’s branded equivalents. The two insulins are insulin lispro protamine and insulin lispro injectable suspension (Humalog Mix 75/25 KwikPen) and insulin lispro injection 100 U/mL (Humalog Junior KwikPen). Read […]

Can Some Insulins Increase Breast Cancer Risk?

A study conducted among Medicare patients looked at whether some forms of insulin and breast cancer risk may be linked in elderly women with diabetes. Read more

Saliva Tests instead of Fingersticks?

Scottish researchers have developed a test using a diabetes patient’s saliva as potential less invasive and painful alternative to the current practice of monitoring blood glucose. Lab tests of the saliva process had an accuracy rate of 95.2%. Read more

Lilly Caps Insulin Prices in Response to Coronavirus

Drugmaker Eli Lilly has announced it has capped the out-of-pocket cost for insulin to $35 per month to help diabetes patients across the United States, many of whom face increased financial difficulties due to the COVID-19 outbreak. This new co-pay scheme covers most of Lilly’s insulins, including the Humalog injection, and is available to people […]