Medical Research

New Artificial Pancreas Trial Shows Benefits for Type 1

Participants with type 1 diabetes in a 12-week clinical trial showed significant improvements in two important health measures. Their HbA1c decreased and the amount of time they spent in hypoglycemia was reduced. The artificial pancreas system consists of an insulin pump and continuous glucose monitor, surgically placed under a patient’s skin, and is designed to […]

Genetic Research May Help Pinpoint Type 1 Risk

Genetic testing may soon play a larger role in diagnosing type 1 diabetes in children and adults, and helping doctors predict who will develop it in the future. While type 1 was long known as “juvenile diabetes,” in fact half of patients develop it after age 30. Genetic researchers believe they will one day be […]

New Study Shows SGLT-2 Inhibitors Have Heart Benefits for Elderly

New research led by the American insurance company Anthem Inc. looked at how the SGLT-2 inhibitor drug class, which includes drugs like Invokana and Jardiance, compares to the drugs in the DPP-4 inhibitor class (such as Januvia and Tradjenta). The study found a significant reduction in heart failure hospitalizations among older patients at risk of […]

Standard Test May Not Detect Diabetes in African-Americans

A common test used to diagnose type 2 diabetes is influenced by 60 genetic variants, according to a study by an international team of scientists. One genetic variant which is found only in African Americans significantly reduces the accuracy of the HbA1c blood test used to diagnose and monitor type 2. As a result, as […]

One Small Benefit for Type 2: Reduced Aortic Aneurysm Risk

Patients with type 2 diabetes were less likely to develop a serious aortic aneurysm, and had better short-term survival after an aortic aneurysm rupture than those without the disease, according to a large study. The new study supports older, smaller studies that suggest diabetes makes the aortic wall stronger. Unfortunately, patients with type 2 still […]

Does Eating Meat and Poultry Increase Diabetes Risk?

A plant-based diet is sometimes considered healthier than a meat-based diet in preventing the risk of diabetes, but not all meats affect the risk equally. A new research study suggests higher intake of red meat and poultry is associated with significantly increased risk of developing diabetes, partially attributed to their higher content of heme iron […]

Can a Single Test find Cancer, Diabetes, and More?

Human blood contains tiny shards of DNA, released as cells die. Cell-free DNA (cfDNA) tests examine these shards. If an analysis can determine where the DNA shards came from, it would be possible to detect damage in different parts of the body. cfDNA tests require only a simple blood draw and could one day be […]

New Treatment May Help Preserve Bone Health in Diabetes

Experiments with a drug compound called TNP (also known as picric acid), used by researchers to study obesity and diabetes, show that in mice the therapy can promote the formation of new bone. This is important as many current drugs that help patients manage their diabetes can also weaken bones, leaving patients more vulnerable to […]

Coronary Bypass Better than Other Treatment Options in Type 1

A new study says that coronary artery bypass surgery (CABG) is the best method of treating artherosclerotic coronary arteries in patients type 1 diabetes and multivessel disease. Current guidelines have recommended CABG over the use of balloon catheters in patients with two or more diseased coronary vessels, but it had not been previously studied whether the benefits […]

Can Machine Learning Help Prevent Type 1?

Tech giant IBM is partnering with JDRF, a global organization that funds Type 1 diabetes research. IBM scientists will look at multiple data sets and apply machine learning algorithms to help find patterns and factors that could influence the development of type 1 diabetes, with the goal of identifying ways that could delay or prevent T1D in children. Read more

A Biochemical “Fingerprint” for Diabetes

Researchers have described a new method to study biochemical changes in the pancreas during the development of diabetes. Their method is based on molecular spectroscopy and can be used to extract biochemical profiles (or ‘fingerprints’) containing information about disease progression. The method could aid in understanding the molecular and cellular  processes that contribute to the development of diabetes. […]

Under-Skin Transplant May Help in Type 1

Researchers say a subcutaneous transplant may show promise in helping patients with Type 1 diabetes. In theory, transplanting insulin-producing cells into the body should be an effective type 1, but in practice finding an environment suitable for the cells has proved challenging. The new research uses a tissue engineering approach to create an environment under the skin. Read more

Liver Inflammation Contributes to Heart Issues for Diabetes Patients

A new study has found that inflammation in the liver can lead to increased cholesterol levels in people with diabetes, contributing to their later development of heart disease. Since cardiovascular problems are a leading cause of death and disability in people with diabetes, the discovery of this previously unknown mechanism could potentially help researchers find […]

Do Diet Drinks and Diet Foods Actually Cause Weight Gain & Diabetes?

Researchers at Yale University say that diet drinks or foods may promote weight gain and trigger diabetes. The brain misreads the number of calories present in the diet food and beverages and reduces metabolism. According to the study, this is due is a ‘mismatch’ between food sweetness and calories. Read more

Most Primary Care Physicians Unable to ID Prediabetes Risk Factors

A recent study set out to assess primary care physicians’ (PCPs) knowledge of risk factors that should prompt prediabetes screening, laboratory criteria for diagnosing prediabetes and guidelines for management of prediabetes. Only 6% of PCPs were able to identify 11 prediabetes risk factors that would prompt them to screen patients under the ADA guidelines. Read […]

Vaccine for Type 1 Will Have Human Trial in 2018

A prototype vaccine will soon be ready for a clinical trial in humans, after two decades of research at the University of Tampere in Finland. Researchers have found evidence linking a type of virus called coxsackievirus B1 with an autoimmune reaction that causes the body to destroy its own pancreatic cells. The vaccine, if successful, […]

New Study Sheds Light on Diabetes and Periodontitis

The University of Pennsylvania study shows diabetes can affect the oral microbiome, potentially causing inflammation, periodontitis and bone loss. The researchers stress the importance of oral hygiene and glycemic control to help counteract these potential effects. Read more

Bariatric Surgery: The Best Cure for Diabetes?

Intestinal bypass surgery is used as a treatment for obesity, but also has the effect of improving or even curing diabetes. Surgeon Francesco Rubino is exploring why the surgery is so effective. It’s not because of weight loss, because the surgery has its effect on diabetes even before the patient loses weight. So what is the mechanism? […]

The Link Between Diabetes and Pancreatic Cancer

Risk of pancreatic cancer rises dramatically among patients newly diagnosed with diabetes. Researcher Richard Frank is leading a study to examine the connection, in the hope of detecting pancreatic cancer earlier, when chances of a cure are higher. Read on

Can Metformin Really Slow Aging?

The diabetes drug metformin is reputed to have many beneficial effects. Researcher Nir Barzilai, director of the Institute for Aging Research at the Albert Einstein College of Medicine in the Bronx, New York, believes it may be able to help us extend our years of healthy, illness-free life. Read more.