Medical Research

Farxiga Not Effective for COVID-19

A large study that tested whether AstraZeneca’s diabetes drug Farxiga showed benefit in treating patients hospitalized with COVID-19 and at risk of developing serious complications did not meet its goals. Read more

Changes in Waist Size Linked to Heart Issues

Obesity is a major risk factor for both cardiovascular disease and metabolic disorders like diabetes. Both BMI and waist circumference are frequently used as gauges of obesity; however, their relationship to weight loss’s effects on different health outcomes has not been well studied. A recent study adds data linking increases in one’s waist circumference to […]

Will Gene Therapy Transform Diabetes Treatment?

Gene therapy has so far been explored mainly in the treatment of rare diseases, but researchers are now turning to how it may be used to treat type 1 diabetes. Gene therapy advocates say the research could transform type 1 treatment, but the research is in its early stages and many obstacles need to be […]

Type 2 Diabetes Linked to Parkinson’s Disease

Researchers say there is convincing evidence that people with type 2 diabetes have an increased risk of developing Parkinson’s disease. Type 2 diabetes is also linked to faster disease progression in patients who already have Parkinson’s. Read more

Stem Cell Therapy for Type 1 Gets FDA Fast-Track

The FDA has granted fast track designation to VX-880, which is a human stem cell-derived therapy for patients with type 1 diabetes. This islet cell therapy is designed to regulate glucose levels by restoring a patient’s pancreatic islet cell function, including insulin production. Read more

Diabetes Med May Treat Parkinson’s Disease

A clinical trial is being conducted in the United Kingdom to investigate whether the diabetes drug exenatide (Byetta) can be used to treat Parkinson’s Disease. Previous research has found that the risk for Parkinson’s is reduced in people who are treated with exenatide for their type 2 diabetes. Read more

An “Inverse Vaccine” for Type 1?

Researchers are investigating a potential “inverse vaccine” for type 1 diabetes. This vaccine would use the body’s anti-inflammatory dendritic cells to retrain the immune system be less damaging to insulin-producing beta cells. If successful, this could be administered to patients in the early stages of type 1 to slow the disease’s progression. Read more

Zinc Could Provide Insight into Diabetes

Because diabetes damages blood vessels, people with diabetes have an increased risk for blood clots, heart attacks, stroke and vascular dementia. Researchers are examining the role of zinc, which helps the blood clot after injury, in these processes. Read more

Diabetes Among Factors that Cause 2/3 of COVID-19 Hospitalizations

About 64% of adults hospitalized with COVID-19 had one or more of four underlying conditions, researchers say: obesity, diabetes, hypertension, and heart failure. This reinforces other studies which have found these conditions are strongly linked to poor COVID-19 outcomes. Read more

Can Electromagnetic Fields Treat Diabetes?

Electromagnetic fields (EMFs) might be a safe and non-invasive way to manage blood glucose in diabetes, say researchers who examined the effects of EMFs in altering the balance of oxidants and antioxidants in the liver and causing an improvement in the body’s response to insulin. Read more

Anemia and A1c

Glycated hemoglobin (A1c) testing is a standard method of assessing blood glucose levels in people with diabetes. However, researchers are finding that iron deficiency or vitamin B12 deficiency anemia can affect A1c testing results. Read more

Stress, Mood Issues Worse in Younger Patients with Diabetes, Sleep Apnea

Obstructive sleep apnea (OSA), insomnia, and diabetes are often linked and can have an impact on quality of life, worsening the risk for stress and depression. New research suggests the impact is worse on people under the age of sixty-five who experience diabetes and OSA. Read more

More Evidence for Heart Benefits of Empagliflozin

Studies of diabetes drugs empagliflozin and dapagliflozin, both in the SGLT-2 inhibitor class, have shown they help reduce cardiovascular risk for diabetes patients. Now, researchers have found that empagliflozin is beneficial for the heart in people without diabetes as well. Read more

Clinical Trial for Possible New Type 1 Treatment

A clinical trial of a new stem cell-derived pancreatic islet cell treatment for type 1 diabetes, by Vertex Pharmaceuticals, is moving forward. According to Vertex, the therapy, called VX-880, has the potential to restore the body’s ability to normalize blood glucose levels through restoration of pancreatic islet cell function. Read more

The Role of Weak and Strong Cells in Insulin Production

Type 2 diabetes is the condition that results when β-cells (beta cells) cannot release enough insulin for the body’s needs. A group of researchers say they have new insight into how “weak” beta cells bond with other, more mature cells to boost insulin production, which can help us understand more about the processes that lead […]

Potential New Target for Diabetes Treatment

Researchers have discovered a new insulin inhibitory receptor, named inceptor. (Insulin receptors are areas in human cells that allow insulin in the blood to join or bind with the cell.) The researchers found that blocking inceptor function makes the insulin signaling pathway in pancreatic beta cells more sensitive, which could potentially allow protection and regeneration […]

Six Types of Prediabetes Identified

Prediabetes is the term for the condition when blood sugar levels are consistently high, but the patient has not yet developed full-blown type 2 diabetes. People with prediabetes are often treated with lifestyle changes such as diet and exercise, and sometimes with medication. However, a team of researchers now say that there are in fact […]

Dexamethasone Less Effective for COVID-19 with Diabetes

Dexamethasone, a steroid being used to treat severe cases of COVID-19, is less effective in treating the coronavirus in people who have diabetes and other risk factors, researchers say. Dexamethasone suppresses the immune system, thus alleviating the damage done to the lungs in patients with an overactive, potentially deadly immune response. Read more

The Link Between Diabetes and Death from COVID-19

Researchers studied the relationship between COVID-19 and patients with diabetes in order to assign a point system to chronic risk factors that can affect COVID-19 cases, including diabetes, obesity, and cardiometabolic disease. Their scoring system can be used to predict the link between COVID, diabetes, and the risk of deaths. Read more

Could Lab-Grown Cells Fight Diabetes?

The immune system fights against dangers like bacteria, viruses, and various other pathogens using a variety of “T cells.” Researchers have engineered a particular type of T cell, called 5MCAR T cells, which they say completely eliminated harmful T cells that invaded the pancreas. These 5MCAR T cells could potentially be used to fight diabetes […]