Medical Research

Accuracy of Key Diabetes Test Varies by Race

The A1C test is a standard way of diagnosing diabetes, by assessing the average levels of glucose attached to red blood cells. However, various genetic factors can affect the accuracy of the test’s results. Now, a new study in patients with type 1 shows that the tests are likely to overestimate the glucose levels of […]

Can a Text Message Lead to Better Diabetes Management?

A new clinical trial has found people with diabetes who received health-related text messages every day for six months showed improvement in their blood glucose levels. The improvement was comparable to that achieved with some diabetes drugs. The trial focused on low-income Hispanics with type 2, and assessed texting as a low-cost intervention that could […]

Can Liraglutide Prevent Diabetes?

A new study found the diabetes drug liraglutide performed better than placebo in reducing the risk that patients with prediabetes would progress to type 2 diabetes, when combined with a program of diet, exercise and weight loss. Read more

Blood Marker Can Predict Heart Attack Risk in People with Diabetes

People with type 2 diabetes are often at increased risk of cardiovascular problems. Researchers have announced that measuring a blood marker called copeptin can successfully predict which patients are at risk, and may be used to prevent heart disease in patients with diabetes. Read more

First Images of Diabetes Receptors May Lead to New Treatments

Researchers have obtained the first cryo-electron microscopy images of a key cellular receptor for diabetes in action. These images provide new information about how G protein-coupled receptors (GPCRs) work. GPCRs conduct molecular messages for most functions in the human body. Read more

$10 Million in Research Funding for Stem Cell Type 1 Treatment

ViaCyte has obtained $10 million in financing to fund the clinical development of its stem cell-derived treatment for type 1 diabetes. The treatment uses stem cell-derived pancreatic cells in an implantable device. The cells are designed to mature into human pancreatic cells, including insulin-secreting beta cells. Read more

How Education is Linked to Diabetes

A study in Germany found those with lower levels of formal education scored higher in most risk factors for diabetes, including obesity, lack of exercise, and poor diet. Read more

Gene Therapy for Type 2?

Gene therapy, in which lab-designed genes are inserted into patients to treat their health conditions, often is focused on type 1 diabetes. However, researchers are now reporting an experiment in using gene therapy to treat type 2 diabetes is showing some success. Read more

One Year of Success with a “Bioengineered Pancreas”

An islet cell transplant, performed at the University of Miami’s Diabetes Research Institute, is proving successful one year later. The islet cells, which produce insulin, were transplanted into a woman whose type 1 diabetes had been difficult for her to manage. Ideally, this research will help identify a suitable location within the body in which […]

Type 1 Cured in Mice?

Researchers believe they have found a way to “trick” the body into curing type 1 diabetes. While much testing remains to be done, they are hopeful this will have a great impact on the future for people with type 1 diabetes, and perhaps have potential to address type 2 as well. Read more

Scientists Closer to Finding Genetic Cause of Type 2

Researchers at University College, London, have reported that they are closer to unlocking the genetic causes of type 2 diabetes after identifying 111 new chromosome locations, in the human genome.  Read more

Electronic Registry Can Help Predict Diabetes Outcomes

Researchers at the 2017 annual meeting of the American Association of Clinical Endocrinologists announced that using a chronic disease registry of nearly 50,000 people with diabetes helped them identify several predictors of better outcomes, including frequent visits with endocrinologists and seeing providers affiliated within the health system. Read more

Diabetes May Affect Brain Function

In a new study, patients with type 2 diabetes scored worse than the healthy controls on tests of memory and reaction times. The problem was worse in overweight diabetes patients than in those of normal weight. Read more

Does Synthetic Biology Offer a Cure for Type 1?

Type 1 diabetes requires constant vigilance. Patients with diabetes must track their blood sugar levels constantly, and calibrate insulin dosage accordingly; and even with constant management the risk of taking too much or too little insulin is always present. Can the field of synthetic biology — which incorporates computer science, engineering, and biology — offer the […]

Obesity Top Cause of Preventable Life-Years Lost

A new study says obesity resulted in up to 47 percent more life-years lost than tobacco or high blood pressure. The study looked at how behavioral risk factors contribute to causes of death among Americans. Obesity and diabetes caused the highest number of preventable life-years lost, followed by tobacco use, high blood pressure and high […]

Smartphones May Learn to Speak to Cells

Researchers have demonstrated a new system in which a smartphone is used to tell engineered cells implanted in diabetic mice to produce insulin. The closed-loop system uses a digital glucometer to transmit data on the rodents’ blood glucose levels to a smartphone. The smartphone processes the data and then signals the implanted cells to deliver insulin. […]

Victoza Tested as Add-on Therapy for DKA in Type 1

A recent study has looked into whether Victoza and other drugs in its class (GLP-1 agonists) can help people with type 1 diabetes to lower their blood glucose levels and lower risk of diabetic ketoacidosis (DKA). The study, conducted by researchers at the Diabetes and Endocrinology Center of Western New York, investigated whether Victoza could reduce production […]

Can Intestinal Bacteria Protect Against Type 2?

A new study from researchers in Finland suggests that a high concentration of indolepropionic acid in the serum protects against type 2 diabetes. Indolepropionic acid is produced by intestinal bacteria, and a diet rich in fiber can help boost its production. According to the researchers, the discovery provides additional insight into the role of intestinal […]

Type 1 Diabetes Risk May Come Down to Gut Bacteria Counts

Diabetes researchers have long noticed that labs have different rates of success breeding mice to have the equivalent of Type 1 diabetes. At first, many scientists attributed this to poor management of genetic drift in some labs, but this theory didn’t hold up. If you transferred a group of mice from a lab with a […]

Fasting Diet Regenerates Beta Cells in Mice

For years, there has been a vocal minority of Type 1 diabetes activists who have claimed that a low-calorie, low-carb diet is a great, but often ignored, treatment option for maintaining blood glucose levels with Type 1 diabetes. Now, a new study may provide strong scientific evidence that such a diet-focused treatment restores beta cell […]