Medical Research

Potential New Way to Regenerate Beta Cells

Pancreatic beta cells, which are essential to insulin production, are reduced by 40-60% in patients with type 2 diabetes, and 70-97% in patients with type 1 diabetes. Researchers have long sought ways to achieve beta cell regeneration in people with diabetes. Recent research suggests a combination of GLP-1 agonists and DYRK1A inhibitors may work to […]

Reducing COVID-19 Complications in Diabetes

Researchers at the University of Michigan have developed an algorithm to help treat COVID-19 patients with diabetes. They hope this algorithm will help reduce the risk of complications like kidney failure and respiratory distress which are more likely to affect people with diabetes & the novel coronavirus. Read more

High Blood Pressure, Diabetes, and Dementia Risk

High blood pressure and diabetes slow down memory and cognition, and the effects can be seen as early as middle age, say researchers who used subtle measurements to determine how the brain is affected in terms of memory and thinking speed at earlier ages. Read more

An Intestinal Film to Block Glucose Uptake

Researchers at Massachusetts Institute of Technology (MIT) have developed a new synthetic film that could help manage diabetes. The material would be consumed as a liquid; the film has the ability to self-assemble in the intestine to block the absorption of glucose, and subsequently dissolve. Read more

New Kind of Treatment for Diabetic Foot Ulcers

Long-term chronic wounds reduce quality of life and can increase risk for death in diabetes patients.  A recent trial found that there was a significant reduction in the size of diabetic foot ulcers (73.1%) with Single Use Negative Pressure Wound Therapy System (sNPWT). Read more

Prediabetes Increases Risk for Heart Disease, Other Complications

Prediabetes is a condition defined by factors like fasting glucose rate and HbA1c levels that are higher than normal, but below the current definition for diabetes. Now, researchers are finding that many complications associated with diabetes, cardiovascular disease and the risk of death, already begin to rise with prediabetes. Read more

Diabetes Increases Parkinson’s Risk

Researchers say they have found evidence that having diabetes may increase the risk of developing Parkinson’s. Diabetes can contribute to the loss of brain cells in Parkinson’s by activating oxidative stress, which is caused by buildup of toxic byproducts of cellular reactions, known as free radicals. Read more

Activating Brown Fat Cells to Fight Diabetes & Obesity

Canadian researchers say they have achieved a scientific breakthrough that could improve the treatment of type 2 diabetes and obesity. They have discovered how to activate brown fat (a tissue responsible for burning calories in excess sugar and fat in the body) in humans. Read more

New-Onset Diabetes After Kidney Transplant

New-onset diabetes after transplantation (NODAT) is a common complication after kidney transplantation, but its mechanism is not fully understood. Researchers in South Korea conducted a study that suggests gut microbiota play a role in the development of NODAT in kidney transplant recipients. Read more

New Research Network to Study Diabetic Foot Ulcers

Six U.S. research institutions are launching a multicenter network, the Diabetic Foot Consortium (DFC), funded by the National Institutes of Health, to study diabetic foot ulcers. Foot ulcers are a common diabetes complication and the leading cause of lower limb amputations in the U.S., and this is the first research network dedicated to studying how […]

“Metabolic Memory” of Poor Glucose Control Can Last a Lifetime

Researchers have found a strong association between early episodes of poor blood sugar control, epigenetic changes (which affect the activity of particular genes without altering their DNA sequences), and diabetic complications years later, even if patients subsequently had better glycemic control. Read more

Long Term Effects of Gastric Bypass & Type 2

A large study of people with type 2 diabetes who had gastric bypass surgery found that their risks for all-cause mortality, cardiovascular disease, acute myocardial infarction, and congestive heart failure were all lower after the surgery. They also had reduced risk of kidney disease, hyperglycemia, cancer, and leg amputations. However, there were also some negative […]

Passive Stretching May Help Prevent Diabetes, Heart Disease

A new study has found passive stretching helps improve blood flow, making it easier for your arteries to dilate and decreasing their stiffness. These findings could have implications for diseases like diabetes and heart disease that involve impaired vascular systems. Read more

Preventing Type 1 May Become a Reality

Teplizumab may become the first antibody commercially available that can halt or delay the progression of type 1 diabetes. Researchers have found that a single 14-day infusion of teplizumab leads to a median 3-year delay in type 1 diabetes onset in high-risk individuals. Read more

Glycemic Control in Young Americans with Diabetes Getting Worse

Blood glucose control among youth with diabetes has not improved since 2002 levels, and has actually gotten worse in some subgroups, according to data presented at the virtual American Diabetes Association (ADA) 2020 Scientific Sessions. This is despite increased availability of diabetes technology and new therapies in recent decades, and despite more aggressive recommended blood […]

Vitamin A Analog May Help Treat Diabetic Retinopathy

Diabetic retinopathy, a common complication of diabetes, is a major cause of blindness in adults. A new study found that visual function in diabetic mice was significantly improved after treatment with a single dose of visual chromophore 9-cis-retinal, a vitamin A analog that can form a visual pigment in the retina cells, thereby producing a […]

“Urgent Need” for More Black Participants in Clinical Trials

Black Americans must be recruited more actively for clinical trial participation, a researcher urges. Data from diabetes clinical trials show that findings often do not apply to blacks and other ethnic minorities in the same way they do to white diabetes patients. Read more

Is Premature Birth Linked to Diabetes Risk?

A new study investigated whether being born prematurely can raise a person’s risks of developing either type 1 or type 2 diabetes from childhood into early to mid-adulthood. Read more

How Gender Impacts Vascular Disease

Both men and women are affected by diabetes, but previous studies have found that women are more affected by macrovascular complications such as coronary artery disease and stroke. It’s not yet known why this is, but the different ways male and female bodies store fat may play a role. Read more

Cortisol Levels May Predict Hypertension, Diabetes

Obesity is a risk factor for many conditions, including type 2 diabetes. Now researchers say obesity may be a result of an alteration in the hypothalamic-pituitary-adrenal (HPA) axis. A recent study examined cortisol levels in people with obesity to determine if there is an association with diabetes, hypertension, and cortisol. Read more