Medical Research

“Super-Grafts” to Treat Severe type 1

To save patients with a severe form of type 1 diabetes, pancreatic cell transplantation is a “last resort” treatment, because the process is long and complex, and many of the grafted cells die quickly. Researchers have found that adding amniotic epithelial cells to these cell clusters creates much more robust “super-islets” of Langerhans. Once transplanted, […]

The Complex Relationship Between Type 2 and Alzheimer’s

Researchers may be only beginning to understand how Alzheimer’s disease and type 2 diabetes could be linked. Deciphering the connection could lead to earlier Alzheimer’s diagnosis and better treatments for both diseases. The connection involves how the brain metabolizes blood sugar and the factors that influence that process, including diet, sleep, and cardiovascular health.   […]

New Test May Help ID Children With Type 1

Nearly one half of all children who develop type 1 diabetes are only diagnosed when they are hospitalized with a diabetic coma. Researchers are trying to see if a genetic test can detect type 1 before these emergencies occur. Read more

Diabetes + Depression Increases Heart Risk

A new study further reinforces that there is an association of type 2 diabetes and depression with heart risk. Patients who have depression and diabetes are at higher risk for all-cause mortality and cardiovascular mortality compared to diabetes patients who do not have depression. Read more

Diabetes and Repeated Heart Failure in Women

Heart failure is a common macrovascular complication that may occur in patients with diabetes. Now, a new study suggests that women with diabetes are more prone to have continuous hospitalization for repeated heart failure problems. Read more

New Eye Scan Could Help Predict Diabetes

New research says that specialist analysis of the lens in the eye can predict which patients may develop type 2 diabetes or impaired glucose tolerance (IGT) or prediabetes. The study used a newly developed biomicroscope which can detect advanced glycation end-products (AGEs) in the eye via a simple scan. Read more

Gene Editing for Obesity and Diabetes?

Researchers are looking into the possibility of using a modified CRISPR gene editing technique to target fat cells, potentially improving weight loss by exploiting how cells use their genetic code. Read more

Pregnant Women with Diabetes at Higher Stillbirth Risk

The reasons for higher stillbirth risk in pregnant women with diabetes are not fully understood, but some risk factors that certainly play a role may be changed, including a pregnant mother’s glucose level and body mass index. Read more

Overtreatment in Medically Complex Diabetes Patients

A large proportion of medically complex patients — patients who have diabetes along with other serious conditions — in the United States are overtreated, leading to more than 9000 excess hospital visits over a 2-year period, researchers say. Read more

Type 2, Menopause, and Sleep Problems

It’s been known that hormone changes can alter insulin sensitivity and glucose metabolism, as well as interfere with women’s sleep patterns. But little research about the association between diabetes and sleep disturbances during menopause had been done. Now, a new study on that topic concludes women with diabetes are at greater risk for sleep disturbances. […]

Obesity and Diabetes Increase Risk for Stillbirth

Pregnant women who have diabetes and obesity are more likely to suffer a stillbirth, according to researchers from the University of Glasgow and the University of Edinburgh in the U.K., who studied a large population of mothers with diabetes in Scotland from 1998-2006. Read more

Fasting Glucose Levels Linked to Pancreatic Cancer

A new study that looked at patient data over more than 5 years found that the risk for pancreatic cancer increased continuously with increased fasting glucose levels, even in people who did not have diabetes. Read more

Metformin Lowers Risk of Dementia for Black Patients

Researchers found that metformin use was associated with a substantially lower risk for dementia among younger African-American patients with diabetes when compared with sulfonylurea, according to a recently published study. Read more

New Type of Diabetes Drug Performs Well in Phase 3 Trial

Imeglimin is the first in a new class of oral antidiabetic agents, the glimins. Imeglimin decreases hepatic glucose production, increases muscle glucose uptake, and improves pancreatic glucose-dependent insulin secretion. The drug performed well in combination with metformin in its latest trial. Read more

Gastric Bypass Beneficial for Adolescents

Researchers have found that the benefits of gastric bypass surgery may be even greater for adolescents with diabetes and obesity than they are for adults. The study findings report that adolescents were 27% more likely than adults to have remission of diabetes after the surgery, and also showed greater reduction in hypertension than adults did. […]

Prediabetes Progression is Not Inevitable

Only 13% of participants in a recent study of patients with elevated blood sugar readings at study start went on to develop diabetes. 64% remained in prediabetes or dropped to normal blood glucose levels without medication, through making lifestyle changes like diet and exercise. Read more

Your Gender Affects Your Risk of Neuropathic Pain

A new study set out to examine how vitamin D deficiencies contribute to neuropathic pain in type 2 diabetes, but the researchers found a surprising result — that vitamin D levels didn’t matter nearly as much to the patients they were studying as did their gender, when it came to pain. Read more

The “Diabetes Bone Paradox” in Type 2

Patients with type 1 diabetes are known to have low bone mineral density (BMD), increasing their risk for bone fractures. In contrast, patients with type 2 diabetes typically have higher BMD — which you might think should reduce their fracture risk. But in fact, people with type 2 have been found to also be at […]

A Protein that Could Reverse Type 2 Diabetes?

Researchers found that in patients who had obesity or were insulin resistant, the gene for a specific glycoprotein, CD248, was upregulated, and the body was making more of the protein. They concluded that CD248 plays a role in the cellular processes that lead to insulin resistance. Read more

Undetected Diabetes Could Double Heart Disease, Gum Disease Risks

It’s long been know that having diabetes contributes to the risk of both periodontitis (gum disease) and heart disease. Researchers recently looked at whether undetected blood sugar disorders (dysglycemia) and undetected diabetes contributed to the conditions, and found they effectively doubled the risk. Read more