Medical Research

Obesity Top Cause of Preventable Life-Years Lost

A new study says obesity resulted in up to 47 percent more life-years lost than tobacco or high blood pressure. The study looked at how behavioral risk factors contribute to causes of death among Americans. Obesity and diabetes caused the highest number of preventable life-years lost, followed by tobacco use, high blood pressure and high […]

Smartphones May Learn to Speak to Cells

Researchers have demonstrated a new system in which a smartphone is used to tell engineered cells implanted in diabetic mice to produce insulin. The closed-loop system uses a digital glucometer to transmit data on the rodents’ blood glucose levels to a smartphone. The smartphone processes the data and then signals the implanted cells to deliver insulin. […]

Victoza Tested as Add-on Therapy for DKA in Type 1

A recent study has looked into whether Victoza and other drugs in its class (GLP-1 agonists) can help people with type 1 diabetes to lower their blood glucose levels and lower risk of diabetic ketoacidosis (DKA). The study, conducted by researchers at the Diabetes and Endocrinology Center of Western New York, investigated whether Victoza could reduce production […]

Can Intestinal Bacteria Protect Against Type 2?

A new study from researchers in Finland suggests that a high concentration of indolepropionic acid in the serum protects against type 2 diabetes. Indolepropionic acid is produced by intestinal bacteria, and a diet rich in fiber can help boost its production. According to the researchers, the discovery provides additional insight into the role of intestinal […]

Type 1 Diabetes Risk May Come Down to Gut Bacteria Counts

Diabetes researchers have long noticed that labs have different rates of success breeding mice to have the equivalent of Type 1 diabetes. At first, many scientists attributed this to poor management of genetic drift in some labs, but this theory didn’t hold up. If you transferred a group of mice from a lab with a […]

Fasting Diet Regenerates Beta Cells in Mice

For years, there has been a vocal minority of Type 1 diabetes activists who have claimed that a low-calorie, low-carb diet is a great, but often ignored, treatment option for maintaining blood glucose levels with Type 1 diabetes. Now, a new study may provide strong scientific evidence that such a diet-focused treatment restores beta cell […]

Where are all the new diabetes drugs?

So has pharma run out of ideas in diabetes? Not exactly. But whether its ideas will ever get to market is another question. There’s plenty of promising science in the early stages of research. Available drugs, however, work pretty well. Given the cost of development and a high bar for approval, pharma can only afford […]

A New Combination Treatment Could Become the Standard T2 Diabetes

A study in Diabetes Care showed that patients with poorly controlled type 2 diabetes who received a combination of exenatide and pioglitazone had a threefold lower rate of hypoglycemia, a one-percentage-point greater reduction in A1C and less weight gain than those in the basal-bolus insulin therapy group.

Research on Remission of Prediabetes to Normal Glucose Tolerance in Obese Adults

This study objective was to determine the effect on remission of prediabetes with a high protein (HP) versus high carbohydrate (HC) diet, and effects on metabolic parameters, and lean and fat body mass in prediabetic, obese subjects after 6 months of dietary intervention. They recruited women and men ages 20–50 years with a BMI ≥ […]

Less shrinkage: This is your aging brain on the Mediterranean diet

New research shows that brain shrinkage is less pronounced in older folks whose diets hew closely to the traditional diet of Mediterranean peoples — including lots of fruits, vegetables, legumes, nuts and olive oil, little red meat and poultry, and regular, moderate consumption of fish and red wine.

Exercise could improve memory loss in type 2 diabetes

A link between moderate aerobic exercise and improving memory loss in people with diabetes has been found in a new study. Researchers from the University of Tsukaba in Japan found four weeks of moderate activity improved memory dysfunction in mouse models of type 2 diabetes.

What is the relationship between diabetes and cognitive decline?

People with diabetes mellitus may be at increased risk for cognitive decline. Correlating these findings with activities of daily living and with degree of DM control is needed, but this study provides further evidence that treating DM may decrease the burden of cognitive decline in older adults.

Can Statins Offset Insulin-Related Cancer Risk in T2DM?

The researchers found that the risk of cancers of the colon (males only), liver (males only), pancreas, lung (males only), and brain (males only) were increased up to nine-fold for patients treated with insulin or insulin secretagogues; the risk of prostate cancer was decreased strongly. The risks were generally decreased for patients taking statins, with […]

Diabetes In Control – How To Drop Blood Sugars By 12%

Researchers concluded that telling patients with type 2 diabetes to “Take a short walk right after meals” may be one of the best exercise prescriptions a clinician can give. Results from the randomized crossover study show that post-meal blood glucose levels dropped 12%, on average, when patients with type 2 diabetes walked for 10 minutes […]

How Your Body Temperature Can Affect Your Metabolism

As humans, we need to generate body heat to keep all of the chemical processes that run our bodies functioning. “Maintaining proper body temperature is crucial,” says Yu Hua Tseng, Ph.D., Principal Investigator in the Section on Integrative Physiology and Metabolism at Joslin Diabetes Center.

Exercise vs. diabetes: New level of detail uncovered

According to the analysis, cycling or walking briskly for 150 minutes each week cuts the risk of developing type 2 diabetes by up to 26 percent. Those who exercise moderately or vigorously for an hour each day reduced their risk by 40 percent. At the other end of the scale, for those who did not […]

Misdiagnosing MODY Diabetes Can Accelerate Beta Cell Destruction

MODY is Maturity-Onset Diabetes of the Young, a form of diabetes that affects 1 percent to 2 percent of those with diabetes. MODY develops before age 25 and is genetically passed from one generation to the next. All children of a parent with MODY have a 50 percent chance of inheriting the gene and being […]

Can a drug eliminate daily injections for Type 2 Diabetics?

A new clinical trial is testing a study drug that could help the T2D community eliminate a daily injection: Key Inclusion / Exclusion Criteria: – Are between 18 and 80 years old – Have a diagnosis of type 2 diabetes – Are taking both metformin and liraglutide (Victoza) – Have a BMI (body mass index) […]

Do You Need More T Cells to Stop Type 1 Diabetes?

A novel treatment meant to stop Type 1 diabetes by increasing the number of T cells in the body is being given special attention by the FDA. The treatment, called CLBS03, has recently been granted Fast Track status by federal regulators, a designation which speeds up the approval process.

BattleDiabetes – Type 2 Diabetes: New Treatment Can Extend Life by Eight Years

This study, published in Diabetologia followed up on the 1993 Steno-2 study. In the Steno-2 a group of 160 people with type 2 diabetes were randomized and treated with either a conventional treatment plan or an intensified treatment plan. The initial study ended after eight years.