Medical Research

Studying the Rarer Forms of Diabetes

While most of us are familiar with type 1 and type 2 diabetes, there are other, rarer forms of the disease, that are poorly understood. A new initiative from the National Institutes of Health (NIH), The Rare and Atypical Diabetes Network (RADIANT) plans to screen about 2,000 people who have unknown or atypical forms of […]

Diabetes in Pregnancy Affects Children’s Future Heart Health

People whose mothers had diabetes during pregnancy are at increased risk for early heart disease as young adults. The researchers say that the risk applies to both children of mothers who have pre-existing type 2 diabetes when they become pregnant, and children whose mothers developed gestational diabetes during their pregnancies. Read more

Vitamin D Deficiency Linked to Painful Neuropathy

Diabetic neuropathy, or nerve damage, is a common diabetes complication, with symptoms that can range from numbness and pain in extremities to decreased functioning of internal organs. Vitamin D deficiency has been linked previously to neuropathy, and now researchers say it has a specific link to painful neuropathy. Read more

Diabetes Drug Jardiance Shows Heart Failure Benefits

Jardiance (empagliflozin) has been studied for its use in people with heart failure. A study has found it shows effectiveness in patients with reduced ejection fraction (HFrEF). In heart failure with reduced ejection fraction, the heart muscle does not contract efficiently, and a smaller percentage of blood is pumped out of the heart than usual. […]

More Insight into Dementia Risks of Type 2

It’s been recognized for some time that 2 diabetes is associated with an increased risk of dementia. A recent large study provides new insight into both the types of dementia implicated and some of the causative factors, finding that the risk is highest for vascular dementia, and the greatest risk is to individuals with poor […]

Diabetes Damages Kidney’s Ability to Clean Itself

The body’s natural process for cleaning its internal organs is called autophagy, which literally means “self-eating.” Researchers say that diabetes can damage the ability of the kidneys to perform this self-cleaning process, which is one reason the kidneys often become bulky and dysfunctional in people with diabetes. Read more

Potential New Way to Regenerate Beta Cells

Pancreatic beta cells, which are essential to insulin production, are reduced by 40-60% in patients with type 2 diabetes, and 70-97% in patients with type 1 diabetes. Researchers have long sought ways to achieve beta cell regeneration in people with diabetes. Recent research suggests a combination of GLP-1 agonists and DYRK1A inhibitors may work to […]

Reducing COVID-19 Complications in Diabetes

Researchers at the University of Michigan have developed an algorithm to help treat COVID-19 patients with diabetes. They hope this algorithm will help reduce the risk of complications like kidney failure and respiratory distress which are more likely to affect people with diabetes & the novel coronavirus. Read more

High Blood Pressure, Diabetes, and Dementia Risk

High blood pressure and diabetes slow down memory and cognition, and the effects can be seen as early as middle age, say researchers who used subtle measurements to determine how the brain is affected in terms of memory and thinking speed at earlier ages. Read more

An Intestinal Film to Block Glucose Uptake

Researchers at Massachusetts Institute of Technology (MIT) have developed a new synthetic film that could help manage diabetes. The material would be consumed as a liquid; the film has the ability to self-assemble in the intestine to block the absorption of glucose, and subsequently dissolve. Read more

New Kind of Treatment for Diabetic Foot Ulcers

Long-term chronic wounds reduce quality of life and can increase risk for death in diabetes patients.  A recent trial found that there was a significant reduction in the size of diabetic foot ulcers (73.1%) with Single Use Negative Pressure Wound Therapy System (sNPWT). Read more

Prediabetes Increases Risk for Heart Disease, Other Complications

Prediabetes is a condition defined by factors like fasting glucose rate and HbA1c levels that are higher than normal, but below the current definition for diabetes. Now, researchers are finding that many complications associated with diabetes, cardiovascular disease and the risk of death, already begin to rise with prediabetes. Read more

Diabetes Increases Parkinson’s Risk

Researchers say they have found evidence that having diabetes may increase the risk of developing Parkinson’s. Diabetes can contribute to the loss of brain cells in Parkinson’s by activating oxidative stress, which is caused by buildup of toxic byproducts of cellular reactions, known as free radicals. Read more

Activating Brown Fat Cells to Fight Diabetes & Obesity

Canadian researchers say they have achieved a scientific breakthrough that could improve the treatment of type 2 diabetes and obesity. They have discovered how to activate brown fat (a tissue responsible for burning calories in excess sugar and fat in the body) in humans. Read more

New-Onset Diabetes After Kidney Transplant

New-onset diabetes after transplantation (NODAT) is a common complication after kidney transplantation, but its mechanism is not fully understood. Researchers in South Korea conducted a study that suggests gut microbiota play a role in the development of NODAT in kidney transplant recipients. Read more

New Research Network to Study Diabetic Foot Ulcers

Six U.S. research institutions are launching a multicenter network, the Diabetic Foot Consortium (DFC), funded by the National Institutes of Health, to study diabetic foot ulcers. Foot ulcers are a common diabetes complication and the leading cause of lower limb amputations in the U.S., and this is the first research network dedicated to studying how […]

“Metabolic Memory” of Poor Glucose Control Can Last a Lifetime

Researchers have found a strong association between early episodes of poor blood sugar control, epigenetic changes (which affect the activity of particular genes without altering their DNA sequences), and diabetic complications years later, even if patients subsequently had better glycemic control. Read more

Long Term Effects of Gastric Bypass & Type 2

A large study of people with type 2 diabetes who had gastric bypass surgery found that their risks for all-cause mortality, cardiovascular disease, acute myocardial infarction, and congestive heart failure were all lower after the surgery. They also had reduced risk of kidney disease, hyperglycemia, cancer, and leg amputations. However, there were also some negative […]

Passive Stretching May Help Prevent Diabetes, Heart Disease

A new study has found passive stretching helps improve blood flow, making it easier for your arteries to dilate and decreasing their stiffness. These findings could have implications for diseases like diabetes and heart disease that involve impaired vascular systems. Read more

Preventing Type 1 May Become a Reality

Teplizumab may become the first antibody commercially available that can halt or delay the progression of type 1 diabetes. Researchers have found that a single 14-day infusion of teplizumab leads to a median 3-year delay in type 1 diabetes onset in high-risk individuals. Read more