Type I

Improving Care for Young Black & Hispanic Type 1 Patients

Healthcare providers need to do more to bring young Black and Hispanic patients with type 1 diabetes into a shared decision-making process, a recent study says. Improving shared decision-making could help reduce racial-ethnic inequity in use of diabetes technology. Read more

COVID-19 Increased DKA Rate in Children with Type 1

A study in Germany found that children with a new diagnosis of type 1 diabetes experienced higher rates of diabetic ketoacidosis (DKA), a dangerous complication of diabetes, during the COVID-19 pandemic. Read more

Insulin Dosing Before Exercise

Exercise is essential for people with diabetes, but it also can contribute to variations in blood sugar levels, depending on the type of exercise, duration, and many other factors. A small pilot study suggests that low insulin with modest hyperglycemia may be better than higher insulin levels when exercising with type 1 diabetes. Read more

FDA Gives Breakthrough Designation to Type 1 Drug

The U.S. Food and Drug Administration (FDA) grants its Breakthrough Therapy designation to new drugs that show promise, to speed up the drugs’ development and review. A new type 1 diabetes drug, vTv Therapeutics’ TTP399, which is being developed as an adjunctive therapy to insulin for type 1 diabetes, has been granted this designation. Read […]

Is There a Link Between having Type 1 and Being Transgender?

Studies suggest that rates of type 1 diabetes are higher among people who are transgender or gender diverse than among the general population. Read more

Will Gene Therapy Transform Diabetes Treatment?

Gene therapy has so far been explored mainly in the treatment of rare diseases, but researchers are now turning to how it may be used to treat type 1 diabetes. Gene therapy advocates say the research could transform type 1 treatment, but the research is in its early stages and many obstacles need to be […]

Sotagliflozin + Insulin for Type 1 Diabetes

SGLT-2 inhibitors like sotagliflozin are antihyperglycemic agents approved in the US for use in patients with type 2 diabetes. However, sotagliflozin is also approved for type 1 diabetes in Europe, and studies have shown that using sotagliflozin along with insulin has benefits in patients with type 1 diabetes. Read more

Could COVID-19 Increase Risk for Type 1 Diabetes?

Researchers have found that certain viral infections may increase the incidence of type 1 diabetes, and are now investigating whether COVID-19 is among them. Learning more about how viruses may lead to diabetes could help develop strategies for prevention. Read more

The Complexities of Miscarriage or Abortion with Type 1 Diabetes

Type 1 diabetes can potentially increase the risk of miscarriage in some circumstances, and the hormonal changes surrounding a pregnancy ended due to miscarriage or abortion can also impact type 1 management. Read more

ADA Urges Stricter A1c Guidelines for Children with Type 1

The American Diabetes Association (ADA) recommends lowering the target hemoglobin A1C (HbA1C) guidelines for children with type 1 diabetes. This is due to the finding that chronically high blood glucose levels in children could lead to higher risk of several serious effects, including abnormal brain development and cardiac issues. Read more

Can Type 1 Diabetes Be Prevented?

Both genetic and environmental risk factors play a vital role in whether a person develops type 1 diabetes. A study looked at the impact of modifiable risk factors, such as obesity, in people who had high genetic risk for type 1. Read more

Stem Cell Therapy for Type 1 Gets FDA Fast-Track

The FDA has granted fast track designation to VX-880, which is a human stem cell-derived therapy for patients with type 1 diabetes. This islet cell therapy is designed to regulate glucose levels by restoring a patient’s pancreatic islet cell function, including insulin production. Read more

An “Inverse Vaccine” for Type 1?

Researchers are investigating a potential “inverse vaccine” for type 1 diabetes. This vaccine would use the body’s anti-inflammatory dendritic cells to retrain the immune system be less damaging to insulin-producing beta cells. If successful, this could be administered to patients in the early stages of type 1 to slow the disease’s progression. Read more

Vitamin D Deficiency Does Not Increase Type 1 Risk

The possible role of Vitamin D levels contributing to diabetes risk has been much discussed. A recent study has found that deficiencies in Vitamin D are not linked to an increased risk of developing type 1 diabetes in Europeans. Read more

How New Technologies Have Changed Living with Type 1 Diabetes

Technology has changed managing type 1 diabetes dramatically over the last 20 years, for both children and adults. Good glucose management is key to preventing many complications of diabetes, and this has been made much easier with the use of continuous glucose monitors, new pump designs, and closed-loop systems. Read more

Clinical Trial for Possible New Type 1 Treatment

A clinical trial of a new stem cell-derived pancreatic islet cell treatment for type 1 diabetes, by Vertex Pharmaceuticals, is moving forward. According to Vertex, the therapy, called VX-880, has the potential to restore the body’s ability to normalize blood glucose levels through restoration of pancreatic islet cell function. Read more

Diabetes Pharma Company Seeks to Reach More Young People with Type 1

Eli Lilly is expanding its existing type 1 diabetes partnership with Life for a Child, with the goal of supporting more than six times as many children in the next 10 years. Lilly plans to expand care to 150,000 young people with diabetes over the next decade, providing free medicine and equipment like reusable pens […]

Metabolic Syndrome in Type 1 Increases Risk for Complications

Metabolic syndrome is the term for a group of risk factors (including abdominal obesity, high triglycerides, and high blood pressure) that have often been discussed in terms of increasing a person’s risk for type 2 diabetes. However, researchers say metabolic syndrome also poses risks for people with type 1, increasing their risk for serious complications […]

Potential New Target for Diabetes Treatment

Researchers have discovered a new insulin inhibitory receptor, named inceptor. (Insulin receptors are areas in human cells that allow insulin in the blood to join or bind with the cell.) The researchers found that blocking inceptor function makes the insulin signaling pathway in pancreatic beta cells more sensitive, which could potentially allow protection and regeneration […]

Why People with Diabetes Experience the “COVID Effect”

It’s been known since the early days of the pandemic that having diabetes increases the risk for severe COVID-19 complications. There are multiple factors that make the combination of diabetes and COVID-19 so serious. Some patients experience an increase in insulin resistance that raises blood glucose levels; plus, COVID-19 is sometimes treated with steroids, and […]