Type I

How New Technologies Have Changed Living with Type 1 Diabetes

Technology has changed managing type 1 diabetes dramatically over the last 20 years, for both children and adults. Good glucose management is key to preventing many complications of diabetes, and this has been made much easier with the use of continuous glucose monitors, new pump designs, and closed-loop systems. Read more

Clinical Trial for Possible New Type 1 Treatment

A clinical trial of a new stem cell-derived pancreatic islet cell treatment for type 1 diabetes, by Vertex Pharmaceuticals, is moving forward. According to Vertex, the therapy, called VX-880, has the potential to restore the body’s ability to normalize blood glucose levels through restoration of pancreatic islet cell function. Read more

Diabetes Pharma Company Seeks to Reach More Young People with Type 1

Eli Lilly is expanding its existing type 1 diabetes partnership with Life for a Child, with the goal of supporting more than six times as many children in the next 10 years. Lilly plans to expand care to 150,000 young people with diabetes over the next decade, providing free medicine and equipment like reusable pens […]

Metabolic Syndrome in Type 1 Increases Risk for Complications

Metabolic syndrome is the term for a group of risk factors (including abdominal obesity, high triglycerides, and high blood pressure) that have often been discussed in terms of increasing a person’s risk for type 2 diabetes. However, researchers say metabolic syndrome also poses risks for people with type 1, increasing their risk for serious complications […]

Potential New Target for Diabetes Treatment

Researchers have discovered a new insulin inhibitory receptor, named inceptor. (Insulin receptors are areas in human cells that allow insulin in the blood to join or bind with the cell.) The researchers found that blocking inceptor function makes the insulin signaling pathway in pancreatic beta cells more sensitive, which could potentially allow protection and regeneration […]

Why People with Diabetes Experience the “COVID Effect”

It’s been known since the early days of the pandemic that having diabetes increases the risk for severe COVID-19 complications. There are multiple factors that make the combination of diabetes and COVID-19 so serious. Some patients experience an increase in insulin resistance that raises blood glucose levels; plus, COVID-19 is sometimes treated with steroids, and […]

Daily Pill Could Help Optimize Insulin Use

New studies have investigated a once-daily pill that can optimize insulin therapy and reduce HbA1c among adults with type 1 diabetes. The pill, a novel liver-selective glucokinase activator, also known as TTP399, showed superior A1c reduction compared to placebo. Read more

Both Type 1 & Type 2 Diabetes Patients Should Be Prioritized for COVID-19 Vaccinations

 People with both type 1 and type 2 diabetes are at similar risk for increased COVID-19 severity, new findings conclude. Therefore, people with either type of diabetes should be prioritized in receiving COVID-19 vaccinations, researchers say. Read more

Metabolic Syndrome Increases Risk for Complications of Type 1

Metabolic syndrome is a group of risk factors that increase a person’s chances of developing type 2 diabetes and heart disease, including abdominal obesity, high triglycerides, low HDL cholesterol, high blood pressure, and high fasting glucose. Researchers say that people with type 1 diabetes and metabolic system are at greater risk of complications like heart […]

Artificial Pancreas in Children with Type 1 Diabetes

An artificial pancreas, also known as a closed-loop system of insulin delivery or an automated insulin delivery system, could potentially improve outcomes and quality of life in children with type 1 diabetes. Currently, less than 20% of children with type 1 diabetes attain the target glycated hemoglobin level of less than 7% that is recommended […]

The Omnipod Horizon System & Children

The Omnipod 5 Horizon System is a hybrid closed loop automated insulin delivery device. It works with a mobile phone or personal diabetes manager. A unique feature of the device is that it uses custom-built glucose control, modifiable based on the time of day; it can also prevent the patient from experiencing a hypoglycemia episode. […]

Societal Factors Drive Diabetes Complications

Two large studies say that the risk of serious diabetes complications isn’t merely driven by an individual’s blood sugar control. Instead, multiple factors, which can include body mass index (BMI), age, gender, and socio-economic factors like income level, insurance coverage and education can affect a person’s risk of developing complications like diabetic neuropathy and cardiac […]

Immunosuppressive Medication Shows Potential for Type 1 Treatment

Golimumab is a human antibody that is used as an immunosuppressive drug (brand name Simponi) and is approved for the treatment of several autoimmune conditions, including ulcerative colitis. Researchers investigated whether golimumab could preserve beta-cell function in young people newly diagnosed with type 1 diabetes. Read more

Hybrid Closed-Loop Systems and Insulin Variability in Children

Young children with type 1 diabetes often have greater insulin variability than do adults, which can lead to more complications and quality of life issues. Researchers investigated whether hybrid closed-loop devices, which deliver insulin automatically by using an algorithm that sensors glucose values in real-time, can help. Read more

Type 1 Can Affect Children’s Cognitive Development

Because children’s brains are growing, they are more susceptible to interference with glucose production and metabolic breakdown, which has several adverse effects. Glucose in the brain is essential to its proper functioning, as the brain requires glucose to incite and feed brain cells. Read more

Mental Health: Type 1 and “Diabetes Burnout”

Many people who have been diagnosed with type 1 diabetes are overwhelmed by the daily physical and mental challenges of managing the condition. This can result in “diabetes burnout,” a dangerous condition where patients are so overwhelmed they neglect to manage their insulin, glucose testing and food choices adequately. Read more

Precision Medicine Achieves Type 1 Reversal

A precision medicine treatment has led to the reversal of a case of type 1 diabetes in a male patient, says a study published in the New England Journal of Medicine. The researchers found the patient had a harmful mutation in a gene called STAT1, and treated the patient with a drug that could inhibit […]

Challenges for Young Diabetes Patients Moving from Pediatric To Adult Care

Adolescents and young adults age 17-23 who have type 1 diabetes are at high risk for negative health outcomes, including poor glycemic control, as they move from pediatric and parental care to independent self-care skills and preparation for adult diabetes care. Researchers are examining how improved communication between young people and health care providers can […]

New International Guidelines for Safe Exercise with Type 1

An international team of experts have laid out the world’s first standard guidance on how people with diabetes can use modern glucose monitoring devices to help them exercise safely. The guidance can be used by healthcare professionals around the world to help people with type 1 diabetes. Read more

Which Type 1 Patients will Experience Partial Remission?

Doctors know that a certain percentage of people with type 1 diabetes will experience what’s called a “partial remission,” after being diagnosed and started on insulin therapy. Partial remission is a period of time in which the patient’s beta–cell function will temporarily be restored. Researchers are seeking to understand what determines which patients will experience this partial […]