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The FDA recently approved Trijardy XR, a tablet that combines three previously approved medications to treat type 2 diabetes: empagliflozin, a sodium-glucose co-transporter 2 (SGLT-2) inhibitor, linagliptin, a dipeptidyl peptidase-4 (DPP4) inhibitor, and metformin hydrochloride, a biguanide. The advantage of combining these agents is that they each have a different mechanism of action, so they lower blood glucose in different ways. Read more