The SGLT2 inhibitors class of diabetes drugs appear to increase the risk of gangrene of the genital area, a rare but potentially fatal side effect. The FDA found 55 cases of the condition, called Fournier gangrene, in people taking three common types of SGTL2 inhibitors, between March 2013 and January 2019. Read more
Results from a new study led by the University of Edinburgh and UCL suggests men taking the medicines dutasteride or finasteride to reduce the symptoms of prostate disease may be more likely to develop type 2 diabetes. Read more
Accidentally changing an insulin pump setting to add a second basal program is easy to do, and reverting to the “home” screen won’t necessarily undo the change. If you’ve been using one setting for a long time, you may need a refresher on how to correctly change to a new setting. Read more
Two widely used drugs for treating an enlarged prostate may increase the risk of developing type 2 diabetes. A study examined of two similar drugs, finasteride (Proscar) and dutasteride (Avodart), in 39,000 men; the 11-year study used 16,000 men taking tamsulosin (Flomax), a different type of drug for B.P.H., as controls. Compared with those using […]
One of the most common adverse events for patients with type 1 diabetes is hypoglycemia. On average, patients with type 1 diabetes have about two symptomatic hypoglycemia episodes each week, but the common symptoms of hypoglycemia often go unnoticed, increasing the risk of severe hypoglycemic events, which can lead to coma or death. Heart rate […]
Taking medication for type 2 diabetes may also help deter the progression of Alzheimer’s disease, researchers say. USC Dornsife psychologists found that patients with untreated diabetes developed signs of Alzheimer’s disease 1.6 times faster than people who did not have diabetes. The stuy compared the rate of developing the pathology for Alzheimer’s disease and dementia […]
Clinical trials are really stopped early, but the phase 3 trial of “Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation” a.k.a. CREDENCE, was halted early due to demonstration of significant heart and kidney benefits for canagflozin, (Invokana, Janssen Pharmaceuticals Inc.). Read more
Many medications can potentially impact your ability to be physically active. Although most drugs do not affect exercise, several common nondiabetes medications do have potential effects on exercise, including statins, beta-blockers, diuretics, vasodilators, and blood thinners. Read more
The surprising effect of bariatric surgery on type 2 diabetes has been known about for years. For many patients, it can effectively send diabetes into remission almost immediately. Yet in many countries around the world, including the United States, fewer than 1% of people eligible for surgery have access to the procedure. Experts want to […]
There’s been much recent discussion about whether taking the diabetes drug metformin has health benefits for people who don’t have diabetes. Some leading experts in diabetes medicine offer their opinions and recommendations on whether or not more people should be taking metformin. Read more
An analysis of the data of 13 studies shows a link between early menopause — entering menopause in your early 40s or earlier — and developing type 2 diabetes. Researchers say this is likely caused by a number of changes that occur during menopause, such as estrogen level changes. Read more
Taking diabetes medication to treat type 2 diabetes may also help keep Alzheimer’s disease away. A recent study found that patients with untreated diabetes developed signs of Alzheimer’s disease 1.6 times faster than people who did not have diabetes. Read more
On March 20, 2019, Novo Nordisk announced the official submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the oral tablet semaglutide, a once-daily glucagon-like peptide-1 (GLP-1) analogue. In trials, oral semaglutide caused reductions in both HbA1c and body weight when compared to placebo. Read more
A study that followed healthy British adults for almost decades found that those who consumed little or no red meat were 11% to 36% less likely to develop type 2 diabetes vs. a large sample of red meat eaters, according to findings published in Nutrition & Diabetes. Read more
Recent studies have shown that even a single episode of diabetic ketoacidosis in young children with type 1 diabetes is associated with lower cognitive scores and altered brain growth; more research is needed to determine the scope of the problem and how to better prevent it. Read more
A new study published in the European Journal of Endocrinology found that women who find their jobs mentally tiring are more likely to develop type 2 diabetes. Mentally draining jobs like teaching increase risk, the researchers say, and employers and women should be more aware of the potential health risks associated with mentally tiring work. Read more
Metformin has not been well studied in patients with impaired kidney function, as it was considered unsafe for use in individuals with moderate or severe chronic kidney disease (CKD). However, the FDA has revised this position, and they have concluded that metformin can be used safely in patients with mild impairment in kidney function and […]
People with schizophrenia have a 20-year shorter lifespan than people without the condition, and diabetes is one cause of this shorter lifespan. Medications for schizophrenia can affect some patient’s with metabolic disturbances: increased weight gain, impaired glucose tolerance and new onset diabetes. Lifestyle risks are also involved, but the direct and indirect effects of the […]
Children of mothers who experienced untreated gestational diabetes during their pregnancies are themselves at risk of insulin resistance and impairment in glucose metabolism, according to a new study. Read more
Study results published in January 2019 examined the effect of probiotic supplements on insulin resistance in pregnant women with diet-controlled gestational diabetes mellitus, and showed potential benefit. Read more